{"id": "package:3df89363-a540-42e8-8abf-3807433a9599", "name": "Optogenetic_summary.pptx", "self_uri": "https://services.scicrunch.io/sparc/drs/v1/objects/3df89363-a540-42e8-8abf-3807433a9599", "size": 2908387, "created_time": "2020-05-22T19:24:56,241447Z", "updated_time": "2022-12-13T15:43:03,032359Z", "version": "3", "mime_type": "application/vnd.openxmlformats-officedocument.presentationml.presentation", "checksums": [{"checksum": "2b58e5d318aaf24dade10c29a4600a3f55baab1b4d299400a4ea226b05287237", "type": "sha256"}], "access_methods": [{"type": "s3", "access_url": {"url": "s3://prd-sparc-discover50-use1/126/files/derivative/Optogenetic_summary.pptx"}, "region": "us-east-1"}], "dataset": {"id": "126", "doi": "DOI:10.26275/xnv0-gtsj", "title": "Optogenetic activation of nitrergic and cholinergic neurons of murine colonic myenteric plexus", "description": "Tension recordings of proximal, middle and distal colon after optogenetic activation of nitrergic and cholinergic myenteric neurons", "abstract": "This dataset examines the effect of optogenetic activation of cholinergic and nitrergic myenteric neurons on motility of the colon, measured by simultaneous tension recordings of the proximal (pC), middle (mC) and distal colon (dC). We examined the effect of optically stimulating (stim) cholinergic and nitrergic neurons expressing the light-activated cation channel channelrhodopsin (ChR2) during a period of tonic inhibition, in between spontaneous colonic migrating motor complexes or CMMCs."}}