{"id": "package:63850421-5b60-4cb2-a57b-63c4beade15a", "name": "0.txt", "self_uri": "https://services.scicrunch.io/sparc/drs/v1/objects/63850421-5b60-4cb2-a57b-63c4beade15a", "size": 74366, "created_time": "2023-03-01T21:50:21,415667Z", "updated_time": "2023-03-01T21:50:30,035030Z", "version": "4", "mime_type": "text/plain", "checksums": [{"checksum": "e3e5915f1a59f09155897299ac18aa78", "type": "sha256"}], "access_methods": [{"type": "s3", "access_url": {"url": "s3://prd-sparc-discover50-use1/311/files/primary/sub-50/sam-2-sub-50/samples/522/slides/0/0/sectionwise2d/fascicles/5/outer/0.txt"}, "region": "us-east-1"}], "dataset": {"id": "311", "doi": "DOI:10.26275/ozlw-crua", "title": "Histology-based computational models of implanted human cervical vagus nerve stimulation with the LivaNova helical cuff electrode", "description": "Computational models and resulting activation thresholds of vagus nerve stimulation with the LivaNova helical cuff, built with ASCENT v1.1.1, using histology from nine human vagus nerves at the mid-cervical level.", "abstract": "To implement, simulate, and analyze computational models of human vagus nerve stimulation with the LivaNova helical cuff to study the effects of fascicle size on fiber activation thresholds We used ASCENT v1.1.1 to build 3D computational models of nine human vagus nerves instrumented with the LivaNova helical cuff electrode. We simulated activation thresholds for 10 um myelinated fibers in response to a 0.5 ms/phase biphasic rectangular pulse. Fibers in larger diameter fascicles have higher activation thresholds than fibers in smaller diameter fascicles."}}